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adapt4pv (version 0.2-2)

Adaptive Approaches for Signal Detection in Pharmacovigilance

Description

A collection of several pharmacovigilance signal detection methods based on adaptive lasso. Additional lasso-based and propensity score-based signal detection approaches are also supplied. See Courtois et al .

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Version

Install

install.packages('adapt4pv')

Monthly Downloads

311

Version

0.2-2

License

GPL-2

Maintainer

Emeline Courtois

Last Published

May 30th, 2022

Functions in adapt4pv (0.2-2)

adapt4pv-package

Adaptive approaches for signal detection in PharmacoVigilance
adapt_cisl

fit an adaptive lasso with adaptive weights derived from CISL
est_ps_hdps

propensity score estimation in high dimension with automated covariates selection using hdPS
data_PV

Simulated data for the adapt4pv package
adapt_univ

fit an adaptive lasso with adaptive weights derived from univariate coefficients
est_ps_xgb

propensity score estimation in high dimension using gradient tree boosting
adapt_cv

fit an adaptive lasso with adaptive weights derived from lasso-cv
est_ps_bic

propensity score estimation in high dimension with automated covariates selection using lasso-bic
adapt_bic

fit an adaptive lasso with adaptive weights derived from lasso-bic
cisl

Class Imbalanced Subsampling Lasso
lasso_bic

fit a lasso regression and use standard BIC for variable selection
ps_adjust

adjustment on propensity score
lasso_perm

fit a lasso regression and use standard permutation of the outcome for variable selection
ps_pond_one

weihting on propensity score for one drug exposure
lasso_cv

wrap function for cv.glmnet
summary_stat

Summary statistics for main adapt4pv package functions
ps_pond

weihting on propensity score
ps_adjust_one

adjustment on propensity score for one drug exposure