affy (version 1.50.0)

generateExprVal.method.playerout: Generate an expression value from the probes informations

Description

Generate an expression from the probes

Usage

generateExprVal.method.playerout(probes, weights=FALSE, optim.method="L-BFGS-B")

Arguments

probes

a list of probes slots from PPSet.container

weights

Should the resulting weights be returned ?

optim.method

see parameter 'optim' for the function optim

Value

A vector of expression values.

Details

A non-parametric method to weight each perfect match probe in the set and to compute a weighted mean of the perfect match values. One will notice this method only makes use of the perfect matches. (see function playerout.costfunction for the cost function).

References

Emmanuel N. Lazaridis, Dominic Sinibaldi, Gregory Bloom, Shrikant Mane and Richard Jove A simple method to improve probe set estimates from oligonucleotide arrays, Mathematical Biosciences, Volume 176, Issue 1, March 2002, Pages 53-58