dual_discrim_shared_likelihood

Frequency estimate of the first alpha-beta clone

est1

Frequency estimate of the second alpha-beta clone

est2

Vector containing the number of cells per well

numb_cells

Vector containing the number of wells with the sample
sizes given by <code>numb_cells</code>

numb_wells

Calculations of the needed binomial coefficients; this is
faster in R than in Rcpp (from my own tests)

binomials

Calculations of the needed multinomial coefficients;
this is way faster in R due to vectorization

multinomials


<code>dual_discrim_shared_likelihood()</code> is used within <code><a rd-options="" href="/link/dual_top?package=alphabetr&version=0.2.2" data-mini-rdoc="alphabetr::dual_top">dual_top</a></code>
to calculate the likelihood that two alpha-beta pairs identified by
<code><a rd-options="" href="/link/bagpipe?package=alphabetr&version=0.2.2" data-mini-rdoc="alphabetr::bagpipe">bagpipe</a></code> sharing the same beta chain derive from a two
distinct clones sharing the same beta chain dual-alpha clone (instead of
a single dual-alpha clone)


Provides algorithms for frequency-based pairing of alpha-beta T
cell receptors.

Edward Lee

alphabetr

Algorithms for High-Throughput Sequencing of Antigen-Specific T
Cells

dual_discrim_shared_likelihood function


<code>dual_discrim_shared_likelihood()</code> is used within <code><a rd-options='' href='dual_top'>dual_top</a></code>
to calculate the likelihood that two alpha-beta pairs identified by
<code><a rd-options='' href='bagpipe'>bagpipe</a></code> sharing the same beta chain derive from a two
distinct clones sharing the same beta chain dual-alpha clone (instead of
a single dual-alpha clone)


dual_discrim_shared_likelihood: Calculate likelihood of two beta-sharing candidate alpha-beta pairs deriving from a dual clone

Description

Usage

Arguments

Value