alphabetr (version 0.2.2)

likelihood_dualdual: Calculate likelihood curve of frequency estimates for a dual-alpha and dual-beta TCR clone

Description

Calculate likelihood curve of frequency estimates for a dual-alpha and dual-beta TCR clone

Usage

likelihood_dualdual(est, err, numb_wells, numb_cells, numb_sample)

Arguments

est

Clonal frequency estimate

err

Mean drop error rate

numb_wells

A vector with the number of wells with the distinct sample sizes

numb_cells

A vector of the distinct sample sizes, i.e. the number of cells per well

numb_sample

A vector with the number of wells of the sample size of the same position of numb_cells that contains both alpha and both betachains the clone

Value

A numeric with the negative log likelihood