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alternativeROC (version 1.0.1)

cinpv: Diagnostic performance: Confidence interval for negative predictive value

Description

This function computes a confidence interval for the negative predictive value from a ROC curve, given the prevalence of the negative outcome.

Usage

cinpv(roc, npv, prevalence, boot.n, quantiles = c(0.5, 0.025, 0.975), ...)

Value

A numeric vector of length 3 containing the median, lower bound, and upper bound of the confidence interval.

Arguments

roc

Object of class pROC.

npv

Negative predictive value.

prevalence

Prevalence of the endpoint in the study population.

boot.n

Number of bootstrap replicates. Default: 2000.

quantiles

Quantiles. Default: c(0.5,.025,.975).

...

Not used.

Details

This function computes a confidence interval for the negative predictive value from a ROC curve, given the prevalence of the negative outcome. The confidence interval is computed using bootstrap resampling.