aroma.core (version 3.1.1)

CbsModel: The CbsModel class

Description

Package: aroma.core Class CbsModel

Object ~~| ~~+--ChromosomalModel ~~~~~~~| ~~~~~~~+--CopyNumberChromosomalModel ~~~~~~~~~~~~| ~~~~~~~~~~~~+--CopyNumberSegmentationModel ~~~~~~~~~~~~~~~~~| ~~~~~~~~~~~~~~~~~+--CbsModel

Directly known subclasses:

public static class CbsModel extends CopyNumberSegmentationModel

This class represents the Circular Binary Segmentation (CBS) model [1].

Usage

CbsModel(cesTuple=NULL, ..., seed=NULL)

Arguments

...

Arguments passed to the constructor of CopyNumberSegmentationModel.

seed

An (optional) integer that if specified will (temporarily) set the random seed each time before calling the segmentation method. For more information, see segmentByCBS().

Fields and Methods

Methods: No methods defined.

Methods inherited from CopyNumberSegmentationModel: fit, getAsteriskTags, getFitFunction, getFullNames, getRegions, getTags, plot, plotCopyNumberRegionLayers, writeRegions

Methods inherited from CopyNumberChromosomalModel: as.character, calculateChromosomeStatistics, calculateRatios, estimateSds, extractRawCopyNumbers, fit, getChromosomeLength, getDataFileMatrix, getMaxNAFraction, getNames, getOptionalArguments, getPairedNames, getRefSetTuple, getReference, getReferenceSetTuple, isPaired, newPlot, plotAxesLayers, plotChromosomesLayers, plotCytobandLayers, plotFitLayers, plotGridHorizontalLayers, plotRawCopyNumbers, plotSampleLayers, setReference

Methods inherited from ChromosomalModel: as.character, fit, getAlias, getAromaGenomeTextFile, getAsteriskTags, getChipType, getChipTypes, getChromosomes, getFullName, getFullNames, getGenome, getGenomeData, getGenomeFile, getListOfAromaUgpFiles, getName, getNames, getParentPath, getPath, getReportPath, getRootPath, getSetTuple, getSets, getTags, indexOf, nbrOfArrays, nbrOfChipTypes, setChromosomes, setGenome

Methods inherited from Object: $, $<-, [[, [[<-, as.character, attach, attachLocally, clearCache, clearLookupCache, clone, detach, equals, extend, finalize, getEnvironment, getFieldModifier, getFieldModifiers, getFields, getInstantiationTime, getStaticInstance, hasField, hashCode, ll, load, names, objectSize, print, save, asThis

References

[1] Olshen, A. B., Venkatraman, E. S., Lucito, R., Wigler, M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 5: 557-572, 2004. [2] Venkatraman, E. S. & Olshen, A. B. A faster circular binary segmentation algorithm for the analysis of array CGH data. Bioinformatics, 2007.

See Also

CopyNumberSegmentationModel.