This is a random subset of data from the Struewing et al. (1997) study of Ashkenazi
jews and breast cancer. The subset consists of pairs of first-degree female
relatives who are also first degree relatives of a proband.
Usage
data("ashkenazi")
Arguments
Format
A data frame with 3920 observations on the following 4 variables.
famID
family ID indicator
brcancer
1 if subject had breast cancer, 0 if not
age
Age at onset of breast cancer, or current age if no breast cancer
mutant
1 if first degree relative proband was a BRCA mutation carrier, 0 if not
References
Moore DF, Chatterjee N, Pee D, and Gail MH (2001) Pseudo-likelihood estimates
of the cumulative risk of an autosomal dominant disease from a kin-cohort
study. Genetic Epidemiology 20, 210-227.)
Struewing JP, Hartge P, Wacholder S, Baker SM, Berlin M, McAdams M, Timmerman MM,
Brody LC, and Tucker MA (1997) The risk of cancer associated with specific
mutations of BRCA1 and BRCA2 among ashkenazi jews.
New England Journal of Medicine 336, 1401-1408.)