enzyme: Enzymatic rate data for the phospholipase protein ExoU
Description
The bacteria Pseudomonas aeruginosa causes disease in human hosts leading to
sepsis and even death in part by secreting lipases (proteins that break down lipids)
into cellular environments. The protein ExoU is a phospholipase produce by particularly
virulent strains of P. aeruginosa. Benson et al. (2009) measured of ExoU enzymatic
activity under varying levels of the fluorescent phospholipase substrate PED6.source
Benson, M. A., Schmalzer, K. M., and D. W. Frank (2009) A sensitive flouresence-based assay for the detection of ExoU mediated PLA2 activity. Clin Chim Acta 411(3-4): 190-197.