ama1c1cpg

Growth inhibition responses from a three arm vaccine trial (Mullen, et al, 2008).

datasets

Gives some hypothesis test functions (sign test, median and other quantile tests, Wilcoxon signed rank test, coefficient of variation test, test of normal variance, test on weighted sums of Poisson [see Fay and Kim <doi:10.1002/bimj.201600111>], sample size for t-tests with different variances and non-equal n per arm, Behrens-Fisher test, nonparametric ABC intervals, Wilcoxon-Mann-Whitney test [with effect estimates and confidence intervals, see Fay and Malinovsky <doi:10.1002/sim.7890>], two-sample melding tests [see Fay, Proschan, and Brittain <doi:10.1111/biom.12231>], one-way ANOVA allowing var.equal=FALSE [see Brown and Forsythe, 1974, Biometrics]), prevalence confidence intervals that adjust for sensitivity and specificity [see Lang and Reiczigel, 2014 <doi:10.1016/j.prevetmed.2013.09.015>] or Bayer, Fay, and Graubard, 2023 <doi:10.48550/arXiv.2205.13494>). The focus is on hypothesis tests that have compatible confidence intervals, but some functions only have confidence intervals (e.g., prevSeSp).

Michael Fay

asht

Applied Statistical Hypothesis Tests

ama1c1cpg function

A data frame with 58 observations on the following 2 variables.<dl>
 <dt><code>vacc</code></dt>
<dd>a factor representing the three arms of the trial. The levels are: <code>20ug+CPG</code> <code>80ug</code> <code>80ug+CPG</code></dd> <dt><code>resp</code></dt>
<dd>a numeric vector giving the response: day 70 sera percent in vitro growth inhibition of the 3D7 malaria parasite.</dd> 
</dl>

Format

Three arm phase 1 malaria vaccine trial — ama1c1cpg

A data frame with 58 observations on the following 2 variables.<dl>
 <dt><code>vacc</code></dt>
<dd>a factor representing the three arms of the trial. The levels are: <code>20ug+CPG</code> <code>80ug</code> <code>80ug+CPG</code></dd>

 <dt><code>resp</code></dt>
<dd>a numeric vector giving the response: day 70 sera percent in vitro growth inhibition of the 3D7 malaria parasite.</dd>

 
</dl>

ama1c1cpg: Three arm phase 1 malaria vaccine trial

Description

Usage

Arguments

Format

References

Examples