invertHillModel

This funciton takes one or more desired response values and determines the
doses that will produce the desired effects given a particular Hill dose
response model. This is useful for estimating things like IC50.

Evaluate, fit, and analyze Hill dose response models (Goutelle et
al., 2008 <doi:10.1111/j.1472-8206.2008.00633.x>), also sometimes referred
to as four-parameter log-logistic models. Includes tools to invert Hill
models, select models based on the Akaike information criterion
(Akaike, 1974 <doi:10.1109/TAC.1974.1100705>) or Bayesian information
criterion (Schwarz, 1978 <https://www.jstor.org/stable/2958889>), and
construct bootstrapped confidence intervals both
on the Hill model parameters and values derived from the Hill model
parameters.

Nathaniel Twarog

basicdrm

Fit Hill Dose Response Models

Anang Shelat

invertHillModel function

<dl><dt>effect</dt>
<dd>A vector of desired response values</dd>
<dt>hpar</dt>
<dd>A four parameter vector specifying the Hill model. Parameter
details are found in the documentation for <code>evalHillModel()</code></dd>
<dt>invalidNA</dt>
<dd>Specifies what to do with values that are outside the range
of the given Hill model. If <code>FALSE</code> (the default), values "below" the given
range will be set to zero, and values "above" the given range will be set to
Inf. If <code>TRUE</code>, invalid values will be set to <code>NA</code>.</dd></dl>

Arguments

Calculates the required doses of a Hill dose response model — invertHillModel

<dl>

<dt>effect</dt>
<dd>A vector of desired response values</dd>


<dt>hpar</dt>
<dd>A four parameter vector specifying the Hill model. Parameter
details are found in the documentation for <code>evalHillModel()</code></dd>


<dt>invalidNA</dt>
<dd>Specifies what to do with values that are outside the range
of the given Hill model. If <code>FALSE</code> (the default), values "below" the given
range will be set to zero, and values "above" the given range will be set to
Inf. If <code>TRUE</code>, invalid values will be set to <code>NA</code>.</dd>

</dl>

invertHillModel: Calculates the required doses of a Hill dose response model

Description

Usage

Value

Arguments

Examples