get_details.bma

Get Details of a BMA Basket Trial Simulation

Provides a unified syntax for the simulation-based comparison of different single-stage basket trial
designs with a binary endpoint and equal sample sizes in all baskets. Methods include the designs by
Baumann et al. (2024) <doi:10.48550/arXiv.2309.06988>, Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>,
Berry et al. (2020) <doi:10.1177/1740774513497539>, Neuenschwander et al. (2016) <doi:10.1002/pst.1730> and
Psioda et al. (2021) <doi:10.1093/biostatistics/kxz014>. For the latter three designs, the functions are mostly
wrappers for functions provided by the packages 'bhmbasket' and 'bmabasket'.

Lukas Baumann

basksim

Simulation-Based Calculation of Basket Trial Operating
Characteristics

Lukas Sauer

get_details.bma function

<dl><dt>design</dt>
<dd>An object of class <code>bma</code>.</dd>
<dt>n</dt>
<dd>The sample size per basket.</dd>
<dt>p1</dt>
<dd>Probabilities used for the simulation. If <code>NULL</code>
then all probabilities are set to p0.</dd>
<dt>lambda</dt>
<dd>The posterior probability threshold.</dd>
<dt>pmp0</dt>
<dd>Power parameter that is used to compute prior probabilities. See
<code>bma</code> for details.</dd>
<dt>iter</dt>
<dd>The number of iterations in the simulation. Is ignored if
<code>data</code> is specified.</dd>
<dt>data</dt>
<dd>A data matrix with k column with the number of responses for each
basket. Has to be generated with <code>get_data</code>. If <code>data</code> is used,
then <code>iter</code> is ignored.</dd>
<dt>...</dt>
<dd>Further arguments.</dd></dl>

Arguments

Get Details of a BMA Basket Trial Simulation — get_details.bma

<dl>

<dt>design</dt>
<dd>An object of class <code>bma</code>.</dd>


<dt>n</dt>
<dd>The sample size per basket.</dd>


<dt>p1</dt>
<dd>Probabilities used for the simulation. If <code>NULL</code>
then all probabilities are set to p0.</dd>


<dt>lambda</dt>
<dd>The posterior probability threshold.</dd>


<dt>pmp0</dt>
<dd>Power parameter that is used to compute prior probabilities. See
<code>bma</code> for details.</dd>


<dt>iter</dt>
<dd>The number of iterations in the simulation. Is ignored if
<code>data</code> is specified.</dd>


<dt>data</dt>
<dd>A data matrix with k column with the number of responses for each
basket. Has to be generated with <code>get_data</code>. If <code>data</code> is used,
then <code>iter</code> is ignored.</dd>


<dt>...</dt>
<dd>Further arguments.</dd>

</dl>

get_details.bma: Get Details of a BMA Basket Trial Simulation

Description

Usage

Value

Arguments

Examples