setup_mmlglobal

Creates an object of class <code>mmlglobal</code>.

Provides a unified syntax for the simulation-based comparison of different single-stage basket trial
designs with a binary endpoint and equal sample sizes in all baskets. Methods include the designs by
Baumann et al. (2024) <doi:10.48550/arXiv.2309.06988>, Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>,
Berry et al. (2020) <doi:10.1177/1740774513497539>, Neuenschwander et al. (2016) <doi:10.1002/pst.1730> and
Psioda et al. (2021) <doi:10.1093/biostatistics/kxz014>. For the latter three designs, the functions are mostly
wrappers for functions provided by the packages 'bhmbasket' and 'bmabasket'.

Lukas Baumann

basksim

Simulation-Based Calculation of Basket Trial Operating
Characteristics

Lukas Sauer

setup_mmlglobal function

<dl><dt>k</dt>
<dd>The number of baskets.</dd>
<dt>p0</dt>
<dd>A common probability under the null hypothesis.</dd>
<dt>shape1</dt>
<dd>First common shape parameter of the beta prior.</dd>
<dt>shape2</dt>
<dd>Second common shape parameter of the beta prior.</dd></dl>

Arguments

Setup mmlglobal Design Object — setup_mmlglobal

<dl>

<dt>k</dt>
<dd>The number of baskets.</dd>


<dt>p0</dt>
<dd>A common probability under the null hypothesis.</dd>


<dt>shape1</dt>
<dd>First common shape parameter of the beta prior.</dd>


<dt>shape2</dt>
<dd>Second common shape parameter of the beta prior.</dd>

</dl>

setup_mmlglobal: Setup mmlglobal Design Object

Description

Usage

Value

Arguments

Details

References

Examples