call_help

call gt helper, calculate mean dbetabinom from all posterior samples

The method models RNA-seq reads using a mixture of 3 beta-binomial distributions to generate posterior probabilities for genotyping bi-allelic single nucleotide polymorphisms. Elena Vigorito, Anne Barton, Costantino Pitzalis, Myles J. Lewis and Chris Wallace (2023) <doi:10.1093/bioinformatics/btad393> "BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing."

Elena Vigorito

bbmix

Bayesian Model for Genotyping using RNA-Seq

Chris Wallace

call_help function

<dl><dt>n</dt>
<dd>counts alt allele</dd>
<dt>m</dt>
<dd>total counts</dd>
<dt>mu</dt>
<dd>vector with posterior draws for mu param</dd>
<dt>lambda</dt>
<dd>vector with posterior draws for lambda param</dd></dl>

Arguments

call gt helper, calculate mean dbetabinom from all posterior samples — call_help

<dl>

<dt>n</dt>
<dd>counts alt allele</dd>


<dt>m</dt>
<dd>total counts</dd>


<dt>mu</dt>
<dd>vector with posterior draws for mu param</dd>


<dt>lambda</dt>
<dd>vector with posterior draws for lambda param</dd>

</dl>

call_help: call gt helper, calculate mean dbetabinom from all posterior samples

Description

Usage

Value

Arguments