biodosetools (version 3.7.2)

calculate_trans_rate_sigurdson: Calculate Sigurdson's translocation rate

Description

Method based on the paper by Sigurdson, A. J. et al. (2008). International study of factors affecting human chromosome translocations. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 652(2), 112-121. <doi:10.1016/j.mrgentox.2008.01.005>.

Usage

calculate_trans_rate_sigurdson(
  cells,
  genome_factor,
  age_value,
  sex_bool = FALSE,
  sex_value = "none",
  smoker_bool = FALSE,
  ethnicity_value = "none",
  region_value = "none"
)

Value

Numeric value of translocation rate.

Arguments

cells

Number of cells N.

genome_factor

Genomic conversion factor.

age_value

Age of the individual.

sex_bool

If TRUE, sex_value will be used.

sex_value

Sex of the individual, either "male" of "female".

smoker_bool

Whether the individual smokes or not.

ethnicity_value

Ethnicity of the individual.

region_value

Region of the individual.

Examples

calculate_trans_rate_sigurdson(
  cells = 1000,
  genome_factor = 0.58,
  age_value = 30,
  sex_bool = FALSE,
  sex_value = "none",
  smoker_bool = FALSE,
  ethnicity_value = "none",
  region_value = "none"
)