dMetselaar_model

Calculates the first derivative of Metselaar model at a given time for
the model parameters provided and the environmental conditions given.

Functions for modelling microbial inactivation under
isothermal or dynamic conditions. The calculations are based on several mathematical models broadly
used by the scientific community and industry. Functions enable to make predictions for cases where the
kinetic parameters are known. It also implements functions for parameter estimation for isothermal and
dynamic conditions. The model fitting capabilities include an Adaptive Monte Carlo method for a Bayesian
approach to parameter estimation.

Alberto Garre

bioinactivation

Mathematical Modelling of (Dynamic) Microbial Inactivation

Pablo S. Fernandez

Jose A. Egea

dMetselaar_model function

<dl><dt>t</dt>
<dd>numeric vector indicating the time of the experiment.</dd>
<dt>x</dt>
<dd>list with the value of N at t.</dd>
<dt>parms</dt>
<dd>parameters for the secondary model. No explicit check of their validity
is performed (see section Model Parameters).</dd>
<dt>temp_profile</dt>
<dd>a function that provides the temperature at a given time.</dd></dl>

Arguments

<div class="sourceCode"></div><pre><code> \deqn{\frac{dN}{dt} = -N \cdot p \cdot (1/D)^p \cdot (t/Delta)^{p-1} }{
 dN/dt = -N * p * (1/D)^p * (t/Delta)^(p-1)} \deqn{D(T) = D_{ref} \cdot 10^{- (T-T_ref)/z} }{
 D(T) = D_R * 10^(- (T-T_ref)/z )}
</code></pre>

Model Equation

<ul>
<li>temp_ref: Reference temperature for the calculation.</li>
<li>D_R: D-value at the reference temperature.</li>
<li>z: z-value.</li>
<li>p: shape factor of the Weibull distribution.</li>
<li>Delta: Scaling parameter</li>
</ul>

Model Parameters

First Derivate of the Metselaar Model — dMetselaar_model

<dl>

<dt>t</dt>
<dd>numeric vector indicating the time of the experiment.</dd>


<dt>x</dt>
<dd>list with the value of N at t.</dd>


<dt>parms</dt>
<dd>parameters for the secondary model. No explicit check of their validity
is performed (see section Model Parameters).</dd>


<dt>temp_profile</dt>
<dd>a function that provides the temperature at a given time.</dd>

</dl>

<div class="sourceCode"><pre><code> \deqn{\frac{dN}{dt} = -N \cdot p \cdot (1/D)^p \cdot (t/Delta)^{p-1} }{
 dN/dt = -N * p * (1/D)^p * (t/Delta)^(p-1)}

 \deqn{D(T) = D_{ref} \cdot 10^{- (T-T_ref)/z} }{
 D(T) = D_R * 10^(- (T-T_ref)/z )}
</code></pre></div>

<ul>
<li>temp_ref: Reference temperature for the calculation.</li>
<li>D_R: D-value at the reference temperature.</li>
<li>z: z-value.</li>
<li>p: shape factor of the Weibull distribution.</li>
<li>Delta: Scaling parameter</li>
</ul>

dMetselaar_model: First Derivate of the Metselaar Model

Description

Usage

Value

Arguments

Model Equation

Model Parameters

Details

See Also