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biospear (version 1.0.0)

Biomarker Selection in Penalized Regression Models

Description

Provides a useful R tool for developing and validating prediction models, estimate expected survival of patients and visualize them graphically. Most of the implemented methods are based on penalized regressions such as: the lasso (Tibshirani R (1996)), the elastic net (Zou H et al. (2005) ), the adaptive lasso (Zou H (2006) ), the stability selection (Meinshausen N et al. (2010) ), some extensions of the lasso (Ternes et al. (2016) ), some methods for the interaction setting (Ternes N et al. (2016) ), or others. A function generating simulated survival data set is also provided.

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Version

Install

install.packages('biospear')

Monthly Downloads

171

Version

1.0.0

License

GPL-2

Maintainer

Nils Ternes

Last Published

May 13th, 2017

Functions in biospear (1.0.0)

selRes

Evaluation of the selection accuracy of a prediction model
simdata

Generation of data sets with survival outcome
BMsel

Biomarker selection in a Cox regression model
Breast

Early breast cancer data
expSurv

Computation of expected survival based on a prediction model
predRes

Evaluation of the prediction accuracy of a prediction model