c212 (version 0.98)

c212.bin.test: Plot Raw Adverse Event Incidence Data

Description

Test the hypothesis that the proportions in two groups are the same. adverse event.

Usage

c212.bin.test(trial.data, alternative = "two.sided", correct = TRUE)

Arguments

trial.data

A file or data frame containing the trial data. The data frame must contain the columns B (body-system), AE (adverse event), Group (1 - control, 2 treatment), Count (total number of events), Total (total number of participants).

alternative

Alternative hypothesis may be "two.sided", "greater" or "less". The default is "two.sided".

correct

Apply a continuity correction.

Value

Dataframe containing the results of the test. A copy of the input dataframe with an additional column p containing the p-value from the test.

Details

Test the hypothesis that the proportions in two groups are the same.

Examples

# NOT RUN {
data(c212.trial.data)
pr = c212.bin.test(c212.trial.data)
head(pr)

# }
# NOT RUN {
          B j       AE            p
1 Bdy-sys_1 1 Adv-Ev_1 2.893605e-01
2 Bdy-sys_2 1 Adv-Ev_2 5.711463e-03
3 Bdy-sys_2 2 Adv-Ev_3 1.655715e-02
4 Bdy-sys_2 3 Adv-Ev_4 6.497695e-01
5 Bdy-sys_2 4 Adv-Ev_5 7.433433e-01
6 Bdy-sys_3 1 Adv-Ev_6 8.419469e-08

# }