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caffsim (version 0.2.2)

Simulation of Plasma Caffeine Concentrations by Using Population Pharmacokinetic Model

Description

Simulate plasma caffeine concentrations using population pharmacokinetic model described in Lee, Kim, Perera, McLachlan and Bae (2015) .

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install.packages('caffsim')

Monthly Downloads

255

Version

0.2.2

License

GPL-3 | file LICENSE

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Maintainer

Sungpil Han

Last Published

August 28th, 2017

Functions in caffsim (0.2.2)

caffPkparamMulti

Create a dataset for simulation of multiple dose of caffeine
caffPlot

Create concentration-time curve after single dose of caffeine
UnitTable

Unit data of PK parameters
caffConcTime

Create a dataset of the concentration-time curve of single oral administration of caffeine
caffOverdose

Calculate a duration of plasma caffeine concentration over specified toxic limits
caffPkparam

Create a dataset for simulation of single dose of caffeine
caffPlotMulti

Create concentration-time curve after multiple doses of caffeine
caffShiny

Run shiny app to interactively simulate plasma caffeine concentration.
caffConcTimeMulti

Create a dataset of the concentration-time curve of multiple dosing of caffeine
caffDescstat

Calculate descriptive statistics of simulated PK parameters