Bootstrap

A generic, easy-to-use and intuitive
pharmacokinetic/pharmacodynamic (PK/PD) simulation platform based on R
packages 'rxode2' and 'mrgsolve'. CAMPSIS provides an abstraction
layer over the underlying processes of writing a PK/PD model,
assembling a custom dataset and running a simulation. CAMPSIS has a
strong dependency to the R package 'campsismod', which allows to
read/write a model from/to files and adapt it further on the fly in
the R environment. Package 'campsis' allows the user to assemble a
dataset in an intuitive manner. Once the user’s dataset is ready, the
package is in charge of preparing the simulation, calling 'rxode2' or
'mrgsolve' (at the user's choice) and returning the results, for the
given model, dataset and desired simulation settings.

Nicolas Luyckx

campsis

Generic PK/PD Simulation Platform CAMPSIS

Bootstrap function

<dl><dt>data</dt>
<dd>data frame to be bootstrapped. It must have a unique identifier column
named according to the specified argument 'id' (default value is 'BS_ID').
Other columns are covariates to bootstrap. They must all be numeric.
Whatever the configuration of the bootstrap, these covariates are always read
row by row and belong to a same individual.</dd>
<dt>id</dt>
<dd>unique identifier column name in data</dd>
<dt>replacement</dt>
<dd>values can be reused or not when drawn, logical</dd>
<dt>random</dt>
<dd>values are drawn randomly, logical</dd>
<dt>export_id</dt>
<dd>tell CAMPSIS if the identifier 'BS_ID' must be output or not, logical</dd></dl>

Arguments

Create a bootstrap object. — Bootstrap

<dl>

<dt>data</dt>
<dd>data frame to be bootstrapped. It must have a unique identifier column
named according to the specified argument 'id' (default value is 'BS_ID').
Other columns are covariates to bootstrap. They must all be numeric.
Whatever the configuration of the bootstrap, these covariates are always read
row by row and belong to a same individual.</dd>


<dt>id</dt>
<dd>unique identifier column name in data</dd>


<dt>replacement</dt>
<dd>values can be reused or not when drawn, logical</dd>


<dt>random</dt>
<dd>values are drawn randomly, logical</dd>


<dt>export_id</dt>
<dd>tell CAMPSIS if the identifier 'BS_ID' must be output or not, logical</dd>

</dl>

Bootstrap: Create a bootstrap object.

Description

Usage

Value

Arguments