vpcPlot

internal

A generic, easy-to-use and intuitive
pharmacokinetic/pharmacodynamic (PK/PD) simulation platform based on
the R packages 'rxode2' and 'mrgsolve'. Campsis provides an
abstraction layer over the underlying processes of defining a PK/PD
model, assembling a custom dataset and running a simulation. The
package has a strong dependency on the R package 'campsismod', which
allows models to be read from and written to files, including through
a JSON-based interface, and to be adapted further on the fly in the R
environment. In addition, 'campsis' allows users to assemble datasets
in an intuitive manner, including via a JSON-based interface to import
Campsis datasets defined using formal JSON schemas distributed with
the package. Once the dataset is ready, the package prepares the
simulation, calls 'rxode2' or 'mrgsolve' (at the user's choice), and
returns the results for the given model, dataset and desired
simulation settings. The package itself is licensed under the GPL (>=
3); the JSON schema files shipped in inst/extdata are licensed
separately under the Creative Commons Attribution 4.0 International
(CC BY 4.0).

Nicolas Luyckx

campsis

Generic PK/PD Simulation Platform Campsis

vpcPlot function

<dl><dt>x</dt>
<dd>data frame, output of Campsis with replicates</dd>
<dt>strata</dt>
<dd>named vector with the strata to use, default is c(SCENARIO="all", ARM="all").
Only columns that are actually present in <code>x</code> are used.</dd>
<dt>level</dt>
<dd>PI level, default is 0.9 (90% PI)</dd>
<dt>alpha</dt>
<dd>alpha parameter (transparency) given to geom_ribbon</dd>
<dt>facet</dt>
<dd>how the stratification variable is displayed. <code>TRUE</code>
(default) draws one panel per stratum with <code>facet_wrap()</code>, keeping the
median band red and the outer bands blue. <code>FALSE</code> overlays the strata
in a single panel, mapping the stratum to the ribbon fill colour (the
median band is drawn more opaque than the outer bands). Ignored when no
stratification is requested.</dd></dl>

Arguments

VPC plot. — vpcPlot

<dl>

<dt>x</dt>
<dd>data frame, output of Campsis with replicates</dd>


<dt>strata</dt>
<dd>named vector with the strata to use, default is c(SCENARIO="all", ARM="all").
Only columns that are actually present in <code>x</code> are used.</dd>


<dt>level</dt>
<dd>PI level, default is 0.9 (90% PI)</dd>


<dt>alpha</dt>
<dd>alpha parameter (transparency) given to geom_ribbon</dd>


<dt>facet</dt>
<dd>how the stratification variable is displayed. <code>TRUE</code>
(default) draws one panel per stratum with <code>facet_wrap()</code>, keeping the
median band red and the outer bands blue. <code>FALSE</code> overlays the strata
in a single panel, mapping the stratum to the ribbon fill colour (the
median band is drawn more opaque than the outer bands). Ignored when no
stratification is requested.</dd>

</dl>

vpcPlot: VPC plot.

Description

Usage

Value

Arguments