mutations

<p>Data frame that contains mutation patterns in multiple genes across multiple patients.</p>

datasets

Functions to perform the following analyses: i) inferring epistasis from RNAi double knockdown data; ii) identifying gene pairs of multiple mutation patterns; iii) assessing association between gene pairs and survival; and iv) calculating the smallworldness of a graph (e.g., a gene interaction network).  Data and analyses are described in Wang, X., Fu, A. Q., McNerney, M. and White, K. P. (2014). Widespread genetic epistasis among breast cancer genes. Nature Communications. 5 4828. <doi:10.1038/ncomms5828>.

Audrey Q Fu

cancerGI

Analyses of Cancer Gene Interaction

mutations function

<p>A data frame with 85 rows and 951 columns.  Each row is a gene.  The first column contains gene names, and each of the other columns contains the mutation pattern in an individual: 0 for no mutation, 1 amplification and -1 deletion.</p>

mutations: Genetic mutation data in patients.

Description

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Examples