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cape (version 2.0.2)

calc.delta.errors: Error propagation

Description

This function performs error propagation on coefficients and standard errors.

Usage

calc.delta.errors(markers,beta.m,se,beta.cov)

Arguments

markers
The marker names being tested
beta.m
The main-effects coefficient matrix for the pairwise regression of the given pair.
se
The standard errors for the marker pair.
beta.cov
The model covariance matrix from the pairwise regression

Value

Returns the error propagated coefficients and standard errors for m12 and m21

References

Carter, G. W., Hays, M., Sherman, A., & Galitski, T. (2012). Use of pleiotropy to model genetic interactions in a population. PLoS genetics, 8(10), e1003010. doi:10.1371/journal.pgen.1003010