get_circle

Given x,y coordinates and a radius, this function
generates points on the circumference of the circle.
This function is used by plot_network to plot cape
results in a circular layout.

internal

Combined Analysis of Pleiotropy and Epistasis infers predictive
networks between genetic variants and phenotypes. It can be used with
standard two-parent populations as well as multi-parent populations, such
as the Diversity Outbred (DO) mice, Collaborative Cross (CC) mice, or the
multi-parent advanced generation intercross (MAGIC) population of Arabidopsis
thaliana. It uses complementary information of pleiotropic gene variants across
different phenotypes to resolve models of epistatic interactions between alleles.
To do this, cape reparametrizes main effect and interaction coefficients from
pairwise variant regressions into directed influence parameters. These
parameters describe how alleles influence each other, in terms of suppression
and enhancement, as well as how gene variants influence phenotypes. All of the
final interactions are reported as directed interactions between pairs of
parental alleles. For detailed descriptions of the methods used in this package
please see the following references.
Carter, G. W., Hays, M., Sherman, A. & Galitski, T. (2012) <doi:10.1371/journal.pgen.1003010>.
Tyler, A. L., Lu, W., Hendrick, J. J., Philip, V. M. & Carter, G. W. (2013) <doi:10.1371/journal.pcbi.1003270>.

Anna L Tyler

cape

Combined Analysis of Pleiotropy and Epistasis for Diversity
Outbred Mice

Anna Tyler

Jake Emerson

Baha El Kassaby

Ann Wells

Georgi Kolishovski

Vivek Philip

Gregory Carter

get_circle function

<dl><dt>radius</dt>
<dd>A numeric value giving the radius of the
circle</dd>
<dt>center_x</dt>
<dd>The x coordinate for the center of the circle</dd>
<dt>center_y</dt>
<dd>The y coordinate for the center of the circle</dd>
<dt>dens</dt>
<dd>A numeric value controlling how many points are returned.
Smaller values will return more points along the circumference of the
circle</dd></dl>

Arguments

Generate coordinates for a circle — get_circle

<dl>

<dt>radius</dt>
<dd>A numeric value giving the radius of the
circle</dd>


<dt>center_x</dt>
<dd>The x coordinate for the center of the circle</dd>


<dt>center_y</dt>
<dd>The y coordinate for the center of the circle</dd>


<dt>dens</dt>
<dd>A numeric value controlling how many points are returned.
Smaller values will return more points along the circumference of the
circle</dd>

</dl>

Generate coordinates for a circle

get_circle: Generate coordinates for a circle

Description

Usage

Value

Arguments