plot_trait_circ

This internal function is called by <code>plot_network</code>
It plots one circle for each trait in the data object.

internal

Combined Analysis of Pleiotropy and Epistasis infers predictive
networks between genetic variants and phenotypes. It can be used with
standard two-parent populations as well as multi-parent populations, such
as the Diversity Outbred (DO) mice, Collaborative Cross (CC) mice, or the
multi-parent advanced generation intercross (MAGIC) population of Arabidopsis
thaliana. It uses complementary information of pleiotropic gene variants across
different phenotypes to resolve models of epistatic interactions between alleles.
To do this, cape reparametrizes main effect and interaction coefficients from
pairwise variant regressions into directed influence parameters. These
parameters describe how alleles influence each other, in terms of suppression
and enhancement, as well as how gene variants influence phenotypes. All of the
final interactions are reported as directed interactions between pairs of
parental alleles. For detailed descriptions of the methods used in this package
please see the following references.
Carter, G. W., Hays, M., Sherman, A. & Galitski, T. (2012) <doi:10.1371/journal.pgen.1003010>.
Tyler, A. L., Lu, W., Hendrick, J. J., Philip, V. M. & Carter, G. W. (2013) <doi:10.1371/journal.pcbi.1003270>.

Anna L Tyler

cape

Combined Analysis of Pleiotropy and Epistasis for Diversity
Outbred Mice

Anna Tyler

Jake Emerson

Baha El Kassaby

Ann Wells

Georgi Kolishovski

Vivek Philip

Gregory Carter

plot_trait_circ function

<dl><dt>trait_circ</dt>
<dd>A list with one element for each cirlce giving
the coordinates of the points to plot for each circle.</dd>
<dt>label_gap</dt>
<dd>The amount of space to leave between the circles
and their labels</dd>
<dt>plot_dim</dt>
<dd>the dimensions of the plot</dd>
<dt>main_lwd</dt>
<dd>The line thickness for the circles</dd></dl>

Arguments

Plot concentric trait circles — plot_trait_circ

<dl>

<dt>trait_circ</dt>
<dd>A list with one element for each cirlce giving
the coordinates of the points to plot for each circle.</dd>


<dt>label_gap</dt>
<dd>The amount of space to leave between the circles
and their labels</dd>


<dt>plot_dim</dt>
<dd>the dimensions of the plot</dd>


<dt>main_lwd</dt>
<dd>The line thickness for the circles</dd>

</dl>

Plot concentric trait circles

plot_trait_circ: Plot concentric trait circles

Description

Usage

Value

Arguments