segment_region

This is an internal function used to segment regions 
for plotting. It returns n evenly spaced points in a given
region. The points can be aligned to the ends of 
the interval, or centered in the interval.

internal

Combined Analysis of Pleiotropy and Epistasis infers predictive
networks between genetic variants and phenotypes. It can be used with
standard two-parent populations as well as multi-parent populations, such
as the Diversity Outbred (DO) mice, Collaborative Cross (CC) mice, or the
multi-parent advanced generation intercross (MAGIC) population of Arabidopsis
thaliana. It uses complementary information of pleiotropic gene variants across
different phenotypes to resolve models of epistatic interactions between alleles.
To do this, cape reparametrizes main effect and interaction coefficients from
pairwise variant regressions into directed influence parameters. These
parameters describe how alleles influence each other, in terms of suppression
and enhancement, as well as how gene variants influence phenotypes. All of the
final interactions are reported as directed interactions between pairs of
parental alleles. For detailed descriptions of the methods used in this package
please see the following references.
Carter, G. W., Hays, M., Sherman, A. & Galitski, T. (2012) <doi:10.1371/journal.pgen.1003010>.
Tyler, A. L., Lu, W., Hendrick, J. J., Philip, V. M. & Carter, G. W. (2013) <doi:10.1371/journal.pcbi.1003270>.

Anna L Tyler

cape

Combined Analysis of Pleiotropy and Epistasis for Diversity
Outbred Mice

Anna Tyler

Jake Emerson

Baha El Kassaby

Ann Wells

Georgi Kolishovski

Vivek Philip

Gregory Carter

segment_region function

<dl><dt>region_min</dt>
<dd>A numerical value indicating the minimum value of the region.</dd>
<dt>region_max</dt>
<dd>A numerical value indicating the maximum value of the region.</dd>
<dt>num_points</dt>
<dd>The number of points to place in the region.</dd>
<dt>alignment</dt>
<dd>A character element indicating whether the points should be 
centered within the region or whether they should extend to the ends of the region.</dd></dl>

Arguments

Divide a region into equal parts. — segment_region

<dl>

<dt>region_min</dt>
<dd>A numerical value indicating the minimum value of the region.</dd>


<dt>region_max</dt>
<dd>A numerical value indicating the maximum value of the region.</dd>


<dt>num_points</dt>
<dd>The number of points to place in the region.</dd>


<dt>alignment</dt>
<dd>A character element indicating whether the points should be 
centered within the region or whether they should extend to the ends of the region.</dd>

</dl>

Divide a region into equal parts.

segment_region: Divide a region into equal parts.

Description

Usage

Value

Arguments