catmapdata

An example data set for use with <code>catmap</code>. All input data should
 have the header as part of the file and either 0 or NA values for entries
 not relevant to that particular study design. For example, TDT studies
 should have the caserisk, controlrisk, casenotrisk and controlnotrisk
 values set to either 0 or NA.

datasets

Although many software tools can perform meta-analyses on genetic case-control data,
none of these apply to combined case-control and family-based (TDT) studies. This package conducts
fixed-effects (with inverse variance weighting) and random-effects [DerSimonian and Laird (1986)
<DOI:10.1016/0197-2456(86)90046-2>] meta-analyses on combined genetic data. Specifically, this package
implements a fixed-effects model [Kazeem and Farrall (2005) <DOI:10.1046/j.1529-8817.2005.00156.x>]
and a random-effects model [Nicodemus (2008) <DOI:10.1186/1471-2105-9-130>] for combined studies.

Thomas Quinn

catmap

Case-Control and TDT Meta-Analysis Package

Kristin Nicodemus

Glaucia Martins

Carlos Maia

catmapdata function

A <code>data.frame</code> with 5 observations and 8 variables.<ul>
<li>name: a factor with study name and optionally year of publication.
 NOTE: if year of publication is included there must be no space between
 study name and year. A comma or underscore works nicely (e.g.,
 <code>Abrams,2001</code> <code>Peter,2002</code> <code>Todd,2003</code>
 <code>Wei,2007</code> <code>Yu,2007</code>)</li>
<li>study: a numeric vector containing 1 if the study is TDT and 2 if the study is case-control</li>
<li>t: a numeric vector containing counts of alleles transmitted in the TDT study</li>
<li>nt: a numeric vector containing counts of alleles not transmitted in the TDT study</li>
<li>caserisk: a numeric vector containing counts of risk alleles in cases</li>
<li>controlrisk: a numeric vector containing counts of risk alleles in controls</li>
<li>casenotrisk: a numeric vector containing counts of non-risk alleles in cases</li>
<li>controlnotrisk: a numeric vector containing counts of non-risk alleles in controls</li>
</ul>

Format

Example <code>catmap</code> Data — catmapdata

Example <code>catmap</code> Data

catmapdata: Example `catmap` Data

Description

Usage

Arguments

Format

See Also