get_diff

The data for the genes which are annotated to the cell-cycle, i.e.
those genes for which "if_cc" is <code>TRUE</code>.

The data for the genes which are not annotated to the cell-cycle,
control genes, genes for which "if_cc" is <code>FALSE</code>

This is an interal function for use by "bootstrap_diff" only.

Implements a method for identifying and removing
the cell-cycle effect from scRNA-Seq data. The description of the
method is in Barron M. and Li J. (2016) <doi:10.1038/srep33892>. Identifying and removing
the cell-cycle effect from single-cell RNA-Sequencing data. Submitted.
Different from previous methods, ccRemover implements a mechanism that
formally tests whether a component is cell-cycle related or not, and thus
while it often thoroughly removes the cell-cycle effect, it preserves
other features/signals of interest in the data.

Jun Li

get_diff: Calculates the average load difference between the cell-cycle genes and control genes for each component.

Description

Usage

Arguments

Value