bdaw

<p>Plasma cortisol area under curve (AUC) was calculated from the trapezoidal rule over the 12-h period of the hourly blood draws. The subjects were required to repeat the process in five visits. The aim of the agreement study was to assess how well the plasma cortisol AUC from hourly measurements agreed with plasma cortisol AUC that was measured every two hours.</p>

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Estimates the Concordance Correlation Coefficient to assess agreement. The scenarios considered are non-repeated measures, non-longitudinal repeated measures (replicates) and longitudinal repeated measures. It also includes the estimation of the one-way intraclass correlation coefficient also known as reliability index. The estimation approaches implemented are variance components and U-statistics approaches. Description of methods can be found in Fleiss (1986) <doi:10.1002/9781118032923> and Carrasco et al. (2013) <doi:10.1016/j.cmpb.2012.09.002>.

Josep Carrasco

bdaw: Blood draw data

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