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cellGeometry (version 0.5.7)

diagnose: Diagnostics for cellMarker signatures

Description

Diagnostic tool which prints information for identifying cell subclasses or groups with weak signatures.

Usage

diagnose(object, group = NULL, angle_cutoff = 30, weak = 2)

Value

No return value. Prints information about the cellMarkers signature showing cells subclasses with weak signatures and diagnostic information including which cell subclasses each problematic signature spills into.

Arguments

object

A 'cellMarkers' or 'deconv' class object.

group

Character vector to focus on cell subclasses within a particular group or groups.

angle_cutoff

Angle in degrees below which cell cluster vectors are considered to overlap too much. Range 0-90. See cos_similarity().

weak

Number of 1st ranked genes for each cell cluster at which/below its gene set is considered weak.