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chlorpromazineR (version 0.2.0)

Convert Antipsychotic Doses to Chlorpromazine Equivalents

Description

As different antipsychotic medications have different potencies, the doses of different medications cannot be directly compared. Various strategies are used to convert doses into a common reference so that comparison is meaningful. Chlorpromazine (CPZ) has historically been used as a reference medication into which other antipsychotic doses can be converted, as "chlorpromazine-equivalent doses". Using conversion keys generated from widely-cited scientific papers, e.g. Gardner et. al 2010 and Leucht et al. 2016 , antipsychotic doses are converted to CPZ (or any specified antipsychotic) equivalents. The use of the package is described in the included vignette. Not for clinical use.

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Install

install.packages('chlorpromazineR')

Monthly Downloads

191

Version

0.2.0

License

GPL-3

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Maintainer

Eric Brown

Last Published

March 14th, 2021

Functions in chlorpromazineR (0.2.0)

to_ap

Calculates equivalent doses
gardner2010

Chlorpromazine equivalent key from Gardner et al. 2010 data
check_key

Check whether a conversion key is the expected format
add_key

Combine 2 keys with base key taking precedence
to_cpz

Calculates chlorpromazine-equivalent doses
leucht2016

Chlorpromazine equivalent key from Leucht et al. 2016 data
davis1974

Chlorpromazine equivalent key from Davis 1974 data
leucht2020

Antipsychotic equivalent key from Leucht et al. 2020 data
gardner2010_withsai

Chlorpromazine equivalent key from Gardner et al. 2010 data
trim_key

Modify the names in a conversion key to only include the first word
check_ap

Checks whether antipsychotic names are in the key
woods2003

Chlorpromazine equivalent key from Woods 2003 data