targetBeta

Find the (a,b) parameters of a scaled Beta distribution with specified 
cummulative probabilities for two specified points from the distribution.

nonlinear

Bayesian and ML Emax model fitting, graphics and simulation for clinical dose
response. The summary data from the dose response meta-analyses in
Thomas, Sweeney, and Somayaji (2014) <doi:10.1080/19466315.2014.924876> and
Thomas and Roy (2016) <doi:10.1080/19466315.2016.1256229>
Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) <doi:10.1177/0962280216684528>
are included
in the package. The prior distributions for the Bayesian analyses default to
the posterior predictive distributions derived from these references.

Neal Thomas

clinDR

Simulation and Analysis Tools for Clinical Dose Response
Modeling

Jing Wu

Mike K. Smith

targetBeta function

<dl> <dt>minval</dt>
<dd>The minimum value with a targetted cummulative probability</dd>
 
 <dt>pminV</dt>
<dd>The targetted cummulative probability less than <code>minval</code></dd> <dt>pmaxV</dt>
<dd>The targetted cummulative probability less than <code>maxval</code></dd> <dt>maxval</dt>
<dd>The maximum value with a targetted cummulative probability</dd>
 
 <dt>aInit</dt>
<dd>An initial guess for the first parameter of the scaled Beta distribution with
 the specified probabilities.</dd> <dt>bInit</dt>
<dd>An initial guess for the second parameter of the scaled Beta distribution with
 the specified probabilities.</dd> <dt>upB</dt>
<dd>The upper limit of the scaled Beta distribution. It is 
 specified by the user.</dd></dl>

Arguments

Author

Find a scaled Beta distribution matching specified probabilities — targetBeta

<dl>

 <dt>minval</dt>
<dd>The minimum value with a targetted cummulative probability</dd>
 
 <dt>pminV</dt>
<dd>The targetted cummulative probability less than <code>minval</code></dd>

 <dt>pmaxV</dt>
<dd>The targetted cummulative probability less than <code>maxval</code></dd>

 <dt>maxval</dt>
<dd>The maximum value with a targetted cummulative probability</dd>
 
 <dt>aInit</dt>
<dd>An initial guess for the first parameter of the scaled Beta distribution with
 the specified probabilities.</dd>

 <dt>bInit</dt>
<dd>An initial guess for the second parameter of the scaled Beta distribution with
 the specified probabilities.</dd>

 <dt>upB</dt>
<dd>The upper limit of the scaled Beta distribution. It is 
 specified by the user.</dd>

</dl>

targetBeta: Find a scaled Beta distribution matching specified probabilities

Description

Usage

Value

Arguments

Author

Details

Examples