auc2dose

Convert AUCtau or AUCt to dose (for 1-compartment linear PK model)

Provides equations commonly used in clinical
pharmacokinetics and clinical pharmacology, such as equations
for dose individualization, compartmental pharmacokinetics,
drug exposure, anthropomorphic calculations, clinical
chemistry, and conversion of common clinical parameters. Where
possible and relevant, it provides multiple published and
peer-reviewed equations within the respective R function.

Ron Keizer

clinPK

Clinical Pharmacokinetics Toolkit

Jasmine Hughes

Dominic Tong

Kara Woo

InsightRX 

auc2dose function

<dl><dt>auc</dt>
<dd>AUCtau</dd>
<dt>CL</dt>
<dd>Clearance</dd>
<dt>V</dt>
<dd>Volume of distribution</dd>
<dt>t_auc</dt>
<dd>if AUCtau is not known but only AUCt, `t_auc` specifies time until which AUC_t is calculated to be able to calculate dose</dd></dl>

Arguments

Convert AUCtau or AUCt to dose (for 1-compartment linear PK model) — auc2dose

<dl>

<dt>auc</dt>
<dd>AUCtau</dd>


<dt>CL</dt>
<dd>Clearance</dd>


<dt>V</dt>
<dd>Volume of distribution</dd>


<dt>t_auc</dt>
<dd>if AUCtau is not known but only AUCt, `t_auc` specifies time until which AUC_t is calculated to be able to calculate dose</dd>

</dl>

auc2dose: Convert AUCtau or AUCt to dose (for 1-compartment linear PK model)

Description

Usage

Arguments

Examples