calc_baseline_scr

Provides equations commonly used in clinical
pharmacokinetics and clinical pharmacology, such as equations
for dose individualization, compartmental pharmacokinetics,
drug exposure, anthropomorphic calculations, clinical
chemistry, and conversion of common clinical parameters. Where
possible and relevant, it provides multiple published and
peer-reviewed equations within the respective R function.

Ron Keizer

clinPK

Clinical Pharmacokinetics Toolkit

Jasmine Hughes

Dominic Tong

Kara Woo

InsightRX 

calc_baseline_scr function

<dl><dt>baseline_scr</dt>
<dd>baseline serum creatinine method (character). See calc_aki_stage() for availabloptions.</dd>
<dt>scr</dt>
<dd>serum creatinine in mg/dL. Use `convert_creat()` to convert from
mmol/L. Values below the detection limit ("&lt;0.2") will be converted to
numeric (0.2)</dd>
<dt>times</dt>
<dd>creatinine sample times in hours</dd>
<dt>method</dt>
<dd>classification method, one of `KDIGO`, `RIFLE`, `pRIFLE` (case insensitive)</dd>
<dt>first_dose_time</dt>
<dd>time in hours of first dose relative to sCr value, used for calculate baseline serum creatinine in `median_before_treatment` approach.</dd>
<dt>verbose</dt>
<dd>verbose (`TRUE` or `FALSE`)</dd></dl>

Arguments

Calculate baseline sCr — calc_baseline_scr

<dl>

<dt>baseline_scr</dt>
<dd>baseline serum creatinine method (character). See calc_aki_stage() for availabloptions.</dd>


<dt>scr</dt>
<dd>serum creatinine in mg/dL. Use `convert_creat()` to convert from
mmol/L. Values below the detection limit ("&lt;0.2") will be converted to
numeric (0.2)</dd>


<dt>times</dt>
<dd>creatinine sample times in hours</dd>


<dt>method</dt>
<dd>classification method, one of `KDIGO`, `RIFLE`, `pRIFLE` (case insensitive)</dd>


<dt>first_dose_time</dt>
<dd>time in hours of first dose relative to sCr value, used for calculate baseline serum creatinine in `median_before_treatment` approach.</dd>


<dt>verbose</dt>
<dd>verbose (`TRUE` or `FALSE`)</dd>

</dl>

Calculate baseline sCr

calc_baseline_scr: Calculate baseline sCr

Description

Usage

Arguments