clinPK (version 0.13.0)

calc_ffm: Calculate fat-free mass

Description

Get an estimate of fat-free mass (FFM, in kg) based on weight, height, and sex (and age for Storset equation).

Usage

calc_ffm(
  weight = NULL,
  bmi = NULL,
  sex = NULL,
  height = NULL,
  age = NULL,
  method = c("janmahasatian", "green", "al-sallami", "storset", "bucaloiu", "hume",
    "james", "garrow_webster"),
  digits = 1
)

Value

Returns a list of the following elements:

value

Fat-free Mass (FFM) in units of kg

unit

Unit describing FFM, (kg)

method

Method used to calculate FFF

Arguments

weight

total body weight in kg

bmi

BMI, only used in `green` method. If `weight` and `height` are both specified, `bmi` will be calculated on-the-fly.

sex

sex, either `male` of `female`

height

height in cm, only required for `holford` method, can be used instead of `bmi` for `green` method

age

age, only used for Storset equation

method

estimation method, one of `janmahasatian` (default), `green`, `al-sallami`, `storset`, `bucaloiu`, `hume`, `james`, or `garrow_webster`.

digits

round to number of digits

Details

References: `janmahasatian`, `green`: Janmahasatian et al. Clin Pharmacokinet. 2005;44(10):1051-65) `al-sallami`: Al-Sallami et al. Clin Pharmacokinet 2015 `storset`: Storset E et al. TDM 2016 `bucaloiu`: Bucaloiu ID et al. Int J of Nephrol Renovascular Dis. 2011 (Morbidly obese females) `hume`: Hume R. J Clin Pathol 1966 `james`: James WPT et al. Research on obesity: a report of the DHSS/MRC Group 1976 `garrow_webster`: Garrow JS, Webster J. Quetelet's index (W/H2) as a measure of fatness. Int J Obesity 1984

Overview: - Sinha J, Duffull1 SB, Al-Sallami HS. Clin Pharmacokinet 2018. https://doi.org/10.1007/s40262-017-0622-5

Examples

calc_ffm(weight = 70, bmi = 25, sex = "male")
calc_ffm(weight = 70, height = 180, age = 40, sex = "female", method = "storset")