clinPK (version 0.13.0)

pk_1cmt_bolus_ss: Concentration predictions for 1-compartmental PK model with bolus dosing at steady state

Description

Concentration predictions for 1-compartmental PK model with bolus dosing at steady state

Usage

pk_1cmt_bolus_ss(t = c(0:24), dose = 100, tau = 12, CL = 3, V = 30, ruv = NULL)

Arguments

t

vector of time

dose

dose

tau

dosing interval

CL

clearance

V

volume of distribution

ruv

residual variability, specified as list with optional arguments for proportional, additive, or exponential components, e.g. `list(prop=0.1, add=1, exp=0)`

Examples

pk_1cmt_bolus_ss(dose = 500, tau = 12, CL = 5, V = 50)
pk_1cmt_bolus_ss(
  dose = 500, tau = 12, CL = 5, V = 50,
  ruv = list(prop = 0.1, add = 0.1))