pk_1cmt_inf_dose_from_cmax

Calculate dose to achieve steady state Cmax
for 1-compartmental PK model with infusion dosing at steady state

Provides equations commonly used in clinical
pharmacokinetics and clinical pharmacology, such as equations
for dose individualization, compartmental pharmacokinetics,
drug exposure, anthropomorphic calculations, clinical
chemistry, and conversion of common clinical parameters. Where
possible and relevant, it provides multiple published and
peer-reviewed equations within the respective R function.

Ron Keizer

clinPK

Clinical Pharmacokinetics Toolkit

Jasmine Hughes

Dominic Tong

Kara Woo

InsightRX 

pk_1cmt_inf_dose_from_cmax function

<dl><dt>cmax</dt>
<dd>desired trough concentration</dd>
<dt>tau</dt>
<dd>dosing interval</dd>
<dt>t_inf</dt>
<dd>infusion time</dd>
<dt>CL</dt>
<dd>clearance</dd>
<dt>V</dt>
<dd>volume of distribution</dd></dl>

Arguments

Calculate dose to achieve steady state Cmax
for 1-compartmental PK model with infusion dosing at steady state — pk_1cmt_inf_dose_from_cmax

<dl>

<dt>cmax</dt>
<dd>desired trough concentration</dd>


<dt>tau</dt>
<dd>dosing interval</dd>


<dt>t_inf</dt>
<dd>infusion time</dd>


<dt>CL</dt>
<dd>clearance</dd>


<dt>V</dt>
<dd>volume of distribution</dd>

</dl>

pk_1cmt_inf_dose_from_cmax: Calculate dose to achieve steady state Cmax for 1-compartmental PK model with infusion dosing at steady state

Description

Usage

Arguments

Examples