pk_2cmt_inf

Concentration predictions for 2-compartmental PK model, single or multiple infusions

Provides equations commonly used in clinical
pharmacokinetics and clinical pharmacology, such as equations
for dose individualization, compartmental pharmacokinetics,
drug exposure, anthropomorphic calculations, clinical
chemistry, and conversion of common clinical parameters. Where
possible and relevant, it provides multiple published and
peer-reviewed equations within the respective R function.

Ron Keizer

clinPK

Clinical Pharmacokinetics Toolkit

Jasmine Hughes

Dominic Tong

Kara Woo

InsightRX 

pk_2cmt_inf function

<dl><dt>t</dt>
<dd>vector of time</dd>
<dt>dose</dt>
<dd>dose</dd>
<dt>tau</dt>
<dd>dosing interval</dd>
<dt>t_inf</dt>
<dd>infusion time</dd>
<dt>CL</dt>
<dd>clearance</dd>
<dt>V</dt>
<dd>volume of central compartment</dd>
<dt>Q</dt>
<dd>inter-compartimental clearance</dd>
<dt>V2</dt>
<dd>volume of peripheral compartment</dd>
<dt>ruv</dt>
<dd>residual error (list)</dd></dl>

Arguments

Concentration predictions for 2-compartmental PK model, single or multiple infusions — pk_2cmt_inf

<dl>

<dt>t</dt>
<dd>vector of time</dd>


<dt>dose</dt>
<dd>dose</dd>


<dt>tau</dt>
<dd>dosing interval</dd>


<dt>t_inf</dt>
<dd>infusion time</dd>


<dt>CL</dt>
<dd>clearance</dd>


<dt>V</dt>
<dd>volume of central compartment</dd>


<dt>Q</dt>
<dd>inter-compartimental clearance</dd>


<dt>V2</dt>
<dd>volume of peripheral compartment</dd>


<dt>ruv</dt>
<dd>residual error (list)</dd>

</dl>

pk_2cmt_inf: Concentration predictions for 2-compartmental PK model, single or multiple infusions

Description

Usage

Arguments