pk_2cmt_t12_interval

Calculate average half-life for 2-compartment model during a specific interval

Provides equations commonly used in clinical
pharmacokinetics and clinical pharmacology, such as equations
for dose individualization, compartmental pharmacokinetics,
drug exposure, anthropomorphic calculations, clinical
chemistry, and conversion of common clinical parameters. Where
possible and relevant, it provides multiple published and
peer-reviewed equations within the respective R function.

Ron Keizer

clinPK

Clinical Pharmacokinetics Toolkit

Jasmine Hughes

Dominic Tong

Kara Woo

InsightRX 

pk_2cmt_t12_interval function

<dl><dt>CL</dt>
<dd>clearance</dd>
<dt>V</dt>
<dd>volume of central compartment</dd>
<dt>Q</dt>
<dd>inter-compartimental clearance</dd>
<dt>V2</dt>
<dd>volume of peripheral compartment</dd>
<dt>tau</dt>
<dd>interval (hours)</dd>
<dt>t_inf</dt>
<dd>infusion time (hours)</dd></dl>

Arguments

Calculate average half-life for 2-compartment model during a specific interval — pk_2cmt_t12_interval

<dl>

<dt>CL</dt>
<dd>clearance</dd>


<dt>V</dt>
<dd>volume of central compartment</dd>


<dt>Q</dt>
<dd>inter-compartimental clearance</dd>


<dt>V2</dt>
<dd>volume of peripheral compartment</dd>


<dt>tau</dt>
<dd>interval (hours)</dd>


<dt>t_inf</dt>
<dd>infusion time (hours)</dd>

</dl>

pk_2cmt_t12_interval: Calculate average half-life for 2-compartment model during a specific interval

Description

Usage

Arguments

Examples