clinfun v1.0.15

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Clinical Trial Design and Data Analysis Functions

Utilities to make your clinical collaborations easier if not fun. It contains functions for designing studies such as Simon 2-stage and group sequential designs and for data analysis such as Jonckheere-Terpstra test and estimating survival quantiles.

Functions in clinfun

Name Description
ktau Kendall's tau-b estimate
roc.perm.test Permutation test to compare ROC curve
toxbdry Stopping rule for toxicity monitoring
twostage.inference Inference following a two-stage design for binary response
ROCanalysis Functions to plot and compare ROC curves.
coxphERR Heller Explained Relative Risk
clinfun-internal Internal clinfun functions
gsdesign Group Sequential Designs
coxphCPE Gonen \& Heller Concordance Probability Estimate
calogrank Survival curves analysis of covariance
roc.curve Empirical ROC curve
aucVardiTest Two-Sample Tests for Growth Curves under Dependent Right Censoring
fedesign Trial Designs Based On Fisher's Exact Test
coxphQuantile Survival time quantile as a function of covariate
jonckheere.test Exact/permutation version of Jonckheere-Terpstra test
power.ladesign Power of k-sample rank test under Lehmann alternative
pselect Probability of selection under pick the winner rule
ph2single Exact single stage Phase II design
deltaAUC Comparing the AUC from ROC curves from nested binary regression
roc.area.test Nonparametric area under the ROC curve
permlogrank Permutation version of survdiff
oc.twostage.bdry Two-stage boundary operating characteristics
ph2simon Simon's 2-stage Phase II design
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License GPL (>= 2)
NeedsCompilation yes
Packaged 2018-04-13 13:50:35 UTC; seshanv
Repository CRAN
Date/Publication 2018-04-13 14:48:39 UTC

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