oc.twostage.bdry

Calculates the operating characteristics of a two-stage boundary.

design

Utilities to make your clinical collaborations easier if not
fun. It contains functions for designing studies such as Simon
2-stage and group sequential designs and for data analysis such
as Jonckheere-Terpstra test and estimating survival quantiles.

Venkatraman E Seshan

clinfun

Clinical Trial Design and Data Analysis Functions

Venkatraman E. Seshan

Karissa Whiting

oc.twostage.bdry function

<dl> <dt>pu</dt>
<dd>unacceptable response rate</dd> <dt>pa</dt>
<dd>response rate that is desirable</dd> <dt>r1</dt>
<dd>first stage threshold to declare treatment undesirable</dd> <dt>n1</dt>
<dd>first stage sample size</dd> <dt>r</dt>
<dd>overall threshold to declare treatment undesirable</dd> <dt>n</dt>
<dd>total sample size</dd></dl>

Arguments

Two-stage boundary operating characteristics — oc.twostage.bdry

<dl>

 <dt>pu</dt>
<dd>unacceptable response rate</dd>

 <dt>pa</dt>
<dd>response rate that is desirable</dd>

 <dt>r1</dt>
<dd>first stage threshold to declare treatment undesirable</dd>

 <dt>n1</dt>
<dd>first stage sample size</dd>

 <dt>r</dt>
<dd>overall threshold to declare treatment undesirable</dd>

 <dt>n</dt>
<dd>total sample size</dd>

</dl>

oc.twostage.bdry: Two-stage boundary operating characteristics

Description

Usage

Value

Arguments