ph2single

Calculates the exact one stage Phase II design

design

Utilities to make your clinical collaborations easier if not
fun. It contains functions for designing studies such as Simon
2-stage and group sequential designs and for data analysis such
as Jonckheere-Terpstra test and estimating survival quantiles.

Venkatraman E Seshan

clinfun

Clinical Trial Design and Data Analysis Functions

Venkatraman E. Seshan

Karissa Whiting

ph2single function

<dl> <dt>pu</dt>
<dd>unacceptable response rate</dd> <dt>pa</dt>
<dd>response rate that is desirable</dd> <dt>ep1</dt>
<dd>threshold for the probability of declaring drug desirable
 under p0</dd> <dt>ep2</dt>
<dd>threshold for the probability of rejecting the drug under
 p1</dd> <dt>nsoln</dt>
<dd>number of designs with given alpha and beta</dd></dl>

Arguments

Exact single stage Phase II design — ph2single

<dl>

 <dt>pu</dt>
<dd>unacceptable response rate</dd>

 <dt>pa</dt>
<dd>response rate that is desirable</dd>

 <dt>ep1</dt>
<dd>threshold for the probability of declaring drug desirable
 under p0</dd>

 <dt>ep2</dt>
<dd>threshold for the probability of rejecting the drug under
 p1</dd>

 <dt>nsoln</dt>
<dd>number of designs with given alpha and beta</dd>

</dl>

ph2single: Exact single stage Phase II design

Description

Usage

Value

Arguments