cliot (version 1.0.0)

abic_alcoholic_hepatitis: ABIC Score for Alcoholic Hepatitis

Description

Calculates the ABIC (Age, Bilirubin, INR, Creatinine) Score to stratify the risk of death at 90 days in patients with alcoholic hepatitis. It categorizes patients into Low, Intermediate, and High risk groups, helping to guide treatment decisions such as the use of corticosteroids.

Usage

abic_alcoholic_hepatitis(age, bilirubin, inr, creatinine,
                         bilirubin_units = "mg/dL", creatinine_units = "mg/dL")

Value

A list containing:

ABIC_Score

The calculated score.

Risk_Group

Risk classification (Low, Intermediate, High).

Est_90_Day_Survival

Estimated survival rate at 90 days based on the validation cohort.

Arguments

age

Numeric. Patient age in years.

bilirubin

Numeric. Serum bilirubin level.

inr

Numeric. International Normalized Ratio.

creatinine

Numeric. Serum creatinine level.

bilirubin_units

String. Units for bilirubin. Options: "mg/dL" (default) or "umol/L".

creatinine_units

String. Units for creatinine. Options: "mg/dL" (default) or "umol/L".

References

Dominguez M, Rincon D, Abraldes JG, et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol. 2008;103(11):2747-2756. doi:10.1111/j.1572-0241.2008.02104.x

Examples

# Example 1: High Risk
# 50yo, Bili 15 mg/dL, INR 2.0, Cr 1.5 mg/dL
# Score = (50*0.1) + (15*0.08) + (1.5*0.3) + (2.0*0.8) = 5 + 1.2 + 0.45 + 1.6 = 8.25 (Intermediate)
abic_alcoholic_hepatitis(50, 15, 2.0, 1.5)

# Example 2: Low Risk
# 40yo, Bili 3 mg/dL, INR 1.1, Cr 0.8 mg/dL
abic_alcoholic_hepatitis(40, 3, 1.1, 0.8)