cliot (version 1.0.0)

acr_eular_ra_2010: ACR/EULAR 2010 Rheumatoid Arthritis Classification Criteria

Description

Calculates the score for the 2010 American College of Rheumatology (ACR) / European League Against Rheumatism (EULAR) Classification Criteria for Rheumatoid Arthritis (RA). A score of 6 or greater (out of 10) classifies a patient as having definite RA.

This criteria set is intended for use in patients who have at least 1 joint with definite clinical synovitis (swelling) and with the synovitis not better explained by another disease.

Usage

acr_eular_ra_2010(joint_involvement, serology, acute_phase_reactants, duration_symptoms)

Value

A list containing:

Total_Score

The calculated classification score (Range 0-10).

Classification

"Definite Rheumatoid Arthritis" if score >= 6, otherwise "Not Classified as Rheumatoid Arthritis".

Arguments

joint_involvement

Numeric. Score for joint involvement. 0: 1 large joint (0 points). 1: 2-10 large joints (1 point). 2: 1-3 small joints (with or without large joints) (2 points). 3: 4-10 small joints (with or without large joints) (3 points). 4: >10 joints (at least 1 small joint) (5 points).

serology

Numeric. Score for Rheumatoid Factor (RF) and Anti-Citrullinated Protein Antibody (ACPA). 0: Negative RF AND negative ACPA (0 points). 1: Low-positive RF OR low-positive ACPA (2 points). 2: High-positive RF OR high-positive ACPA (3 points). (Negative: <= ULN; Low-positive: > ULN but <= 3x ULN; High-positive: > 3x ULN).

acute_phase_reactants

Numeric. Score for Acute-Phase Reactants (CRP and ESR). 0: Normal CRP AND normal ESR (0 points). 1: Abnormal CRP OR abnormal ESR (1 point).

duration_symptoms

Numeric. Duration of synovitis symptoms. 0: < 6 weeks (0 points). 1: >= 6 weeks (1 point).

References

Aletaha D, Neogi T, Silman AJ, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62(9):2569-2581. doi:10.1002/art.27584

Examples

# Example 1: Definite RA
# 4-10 small joints (3 pts), High-positive RF (3 pts), Normal CRP (0 pts), <6 weeks (0 pts)
# Total = 6
acr_eular_ra_2010(3, 2, 0, 0)

# Example 2: Not Classified
# 1-3 small joints (2 pts), Negative Serology (0 pts), Abnormal CRP (1 pt), >=6 weeks (1 pt)
# Total = 4
acr_eular_ra_2010(2, 0, 1, 1)