cliot (version 1.0.0)

adhere_algorithm: ADHERE Algorithm for Acute Decompensated Heart Failure

Description

Implements the classification regression tree (CART) analysis from the Acute Decompensated Heart Failure National Registry (ADHERE). This algorithm uses admission Blood Urea Nitrogen (BUN), Systolic Blood Pressure (SBP), and Serum Creatinine to stratify patients into four risk groups for in-hospital mortality.

Usage

adhere_algorithm(bun, sbp, creatinine)

Value

A list containing:

Risk_Group

The risk classification (Low, Intermediate, High, or Very High).

In_Hospital_Mortality_Risk

The estimated in-hospital mortality percentage associated with the specific node in the validation set.

Arguments

bun

Numeric. Blood Urea Nitrogen in mg/dL. (The first splitting node is at 43 mg/dL).

sbp

Numeric. Systolic Blood Pressure in mmHg. (The second splitting node is at 115 mmHg).

creatinine

Numeric. Serum Creatinine in mg/dL. (The third splitting node is at 2.75 mg/dL).

References

Fonarow GC, Adams KF Jr, Abraham WT, et al. Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis. JAMA. 2005;293(5):572-580. doi:10.1001/jama.293.5.572

Examples

# Example 1: Low Risk (BUN < 43)
adhere_algorithm(bun = 30, sbp = 120, creatinine = 1.0)

# Example 2: Very High Risk (BUN >= 43, SBP < 115, Cr >= 2.75)
adhere_algorithm(bun = 50, sbp = 100, creatinine = 3.0)