cliot (version 1.0.0)

asdas_crp: Ankylosing Spondylitis Disease Activity Score with CRP (ASDAS-CRP)

Description

Calculates the ASDAS-CRP score, a composite index to assess disease activity in patients with Ankylosing Spondylitis (AS). It combines patient-reported outcomes (Back Pain, Morning Stiffness, Global Assessment, Peripheral Pain) with an objective inflammatory marker (CRP).

Usage

asdas_crp(back_pain, duration_morning_stiffness, patient_global,
          peripheral_pain_swelling, crp_mg_l)

Value

A list containing:

ASDAS_CRP_Score

The calculated score.

Disease_Activity_State

Classification (Inactive < 1.3, Moderate < 2.1, High <= 3.5, Very High > 3.5).

Arguments

back_pain

Numeric (0-10). Severity of back pain (BASDAI Question 2).

duration_morning_stiffness

Numeric (0-10). Duration of morning stiffness (BASDAI Question 6).

patient_global

Numeric (0-10). Patient global assessment of disease activity.

peripheral_pain_swelling

Numeric (0-10). Severity of peripheral pain/swelling (BASDAI Question 3).

crp_mg_l

Numeric. C-Reactive Protein level in mg/L. (Note: If CRP < 2 mg/L, it is set to 2 for calculation).

References

Lukas C, Landewe R, Sieper J, et al. Development of an ASAS-endorsed disease activity score for ankylosing spondylitis (ASDAS). Ann Rheum Dis. 2009;68(1):18-24. doi:10.1136/ard.2008.094870

Examples

# Example 1: High Disease Activity
# Back Pain 6, Stiffness 5, Global 6, Peripheral 4, CRP 10
asdas_crp(6, 5, 6, 4, 10)

# Example 2: Inactive Disease
# All scores 1, CRP 1.0
asdas_crp(1, 1, 1, 1, 1)