cliot (version 1.0.0)

atria_bleeding_risk: ATRIA Bleeding Risk Score

Description

Calculates the ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Bleeding Risk Score. This tool stratifies the risk of major hemorrhage in patients with atrial fibrillation who are taking warfarin. It outperforms the HAS-BLED score in predicting major bleeding events.

Usage

atria_bleeding_risk(age, sex, hemoglobin_g_dl, egfr_ml_min, prior_bleeding, hypertension)

Value

A list containing:

ATRIA_Score

The calculated risk score (Range 0-10).

Risk_Category

Classification (Low: 0-3, Intermediate: 4, High: >4).

Annual_Major_Bleeding_Risk

Estimated annual rate of major hemorrhage.

Arguments

age

Numeric. Patient age in years. (>= 75 years adds +2 points).

sex

String. Patient sex ("Male" or "Female"). Used to define anemia thresholds.

hemoglobin_g_dl

Numeric. Hemoglobin level in g/dL. Anemia (<13 g/dL in men, <12 g/dL in women) adds +3 points.

egfr_ml_min

Numeric. Estimated Glomerular Filtration Rate (eGFR) in mL/min/1.73m^2. Severe renal disease (<30 mL/min) adds +3 points.

prior_bleeding

Numeric (0 or 1). History of prior hemorrhage diagnosis. (1 = Yes, +1 point).

hypertension

Numeric (0 or 1). History of hypertension. (1 = Yes, +1 point).

References

Fang MC, Go AS, Chang Y, et al. A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study. J Am Coll Cardiol. 2011;58(4):395-401. doi:10.1016/j.jacc.2011.03.031

Examples

# Example 1: High Risk
# 80yo Male (+2), Hgb 11 (+3), eGFR 25 (+3), No Bleed, HTN (+1)
# Score = 9
atria_bleeding_risk(80, "male", 11, 25, 0, 1)

# Example 2: Low Risk
# 65yo Female (0), Hgb 13 (0), eGFR 60 (0), No Bleed, No HTN
# Score = 0
atria_bleeding_risk(65, "female", 13, 60, 0, 0)