cliot (version 1.0.0)

berlin_ards_criteria: Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS)

Description

Applies the Berlin Definition to diagnostic criteria for ARDS. It evaluates timing, chest imaging, origin of edema, and oxygenation status to classify patients into Mild, Moderate, or Severe ARDS.

Usage

berlin_ards_criteria(timing_within_1_week, bilateral_opacities,
                     edema_not_cardiac, pao2_fio2_ratio, peep_or_cpap)

Value

A list containing:

Classification

The severity class (Mild, Moderate, Severe, or Not ARDS).

Predicted_Mortality

Estimated mortality risk based on the Berlin derivation cohort.

Failure_Reasons

List of specific criteria that were not met.

Arguments

timing_within_1_week

Numeric (0 or 1). Onset within 1 week of a known clinical insult or new/worsening respiratory symptoms. (1 = Yes).

bilateral_opacities

Numeric (0 or 1). Bilateral opacities on CXR or CT not fully explained by effusions, lobar/lung collapse, or nodules. (1 = Yes).

edema_not_cardiac

Numeric (0 or 1). Respiratory failure not fully explained by cardiac failure or fluid overload. (1 = Yes).

pao2_fio2_ratio

Numeric. Ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2/FiO2) in mmHg. Mild: 200 < Ratio <= 300. Moderate: 100 < Ratio <= 200. Severe: Ratio <= 100.

peep_or_cpap

Numeric. Positive End-Expiratory Pressure (PEEP) or Continuous Positive Airway Pressure (CPAP) in cmH2O. Must be >= 5 for diagnosis.

References

The ARDS Definition Task Force. Acute Respiratory Distress Syndrome: The Berlin Definition. JAMA. 2012;307(23):2526-2533. doi:10.1001/jama.2012.5669

Examples

# Example 1: Severe ARDS
# Acute onset, Bilateral infiltrates, Non-cardiac, PF Ratio 80, PEEP 10
berlin_ards_criteria(1, 1, 1, 80, 10)

# Example 2: Not ARDS (PF Ratio too high)
# PF Ratio 350
berlin_ards_criteria(1, 1, 1, 350, 5)

# Example 3: Not ARDS (PEEP too low)
# PEEP 2
berlin_ards_criteria(1, 1, 1, 150, 2)