cliot (version 1.0.0)

bwh_egg_freezing_tool: BWH Egg Freezing Counseling Tool (EFCT)

Description

Calculates the likelihood of achieving at least one, two, or three live births from elective oocyte cryopreservation (egg freezing). The model is based on data from Brigham and Women's Hospital (BWH) and accounts for the patient's age at retrieval and the number of mature oocytes frozen. It estimates the probability based on age-specific oocyte-to-blastocyst and blastocyst-to-euploidy conversion rates.

Usage

bwh_egg_freezing_tool(age, num_mature_eggs)

Value

A list containing:

Likelihood_Live_Birth

A list of probabilities (%) for having at least 1, 2, or 3 live births.

Model_Efficiency_Per_Egg

The approximate probability of a single egg resulting in a live birth for the given age.

Arguments

age

Numeric. The patient's age at the time of egg freezing (Valid range: 24-44 years).

num_mature_eggs

Numeric. The number of mature (MII) oocytes frozen.

References

Goldman RH, Racowsky C, Farland LV, et al. Predicting the likelihood of live birth for elective oocyte cryopreservation: a counseling tool for physicians and patients. Hum Reprod. 2017;32(4):853-859. doi:10.1093/humrep/dex008

Examples

# Example 1: 35-year-old with 10 eggs
# Expected: ~69% chance of at least 1 live birth
bwh_egg_freezing_tool(35, 10)

# Example 2: 40-year-old with 20 eggs
# Expected: ~51% chance of at least 1 live birth
bwh_egg_freezing_tool(40, 20)