cliot (version 1.0.0)

child_pugh_score: Child-Pugh Score for Cirrhosis Mortality

Description

Calculates the Child-Pugh Score (also known as the Child-Turcotte-Pugh Score) to assess the prognosis of chronic liver disease, primarily cirrhosis. The score aggregates five clinical and laboratory measures to categorize patients into Class A, B, or C, which correlates with 1- and 2-year survival rates.

Usage

child_pugh_score(bilirubin, albumin, inr, ascites, encephalopathy,
                 pbc_or_psc = 0, bilirubin_units = "mg/dL",
                 albumin_units = "g/dL")

Value

A list containing:

Child_Pugh_Score

The total calculated score (Range 5-15).

Class

The Child-Pugh Class (A, B, or C).

Life_Expectancy_1_Year

Estimated 1-year survival rate.

Life_Expectancy_2_Year

Estimated 2-year survival rate.

Arguments

bilirubin

Numeric. Total bilirubin level.

albumin

Numeric. Serum albumin level.

inr

Numeric. International Normalized Ratio (INR).

ascites

String. Degree of ascites. Options: "none" (+1 pt), "slight" (Supressed with meds, +2 pts), "moderate" (Refractory, +3 pts).

encephalopathy

String. Degree of encephalopathy. Options: "none" (+1 pt), "grade_1_2" (or medically controlled, +2 pts), "grade_3_4" (or poorly controlled, +3 pts).

pbc_or_psc

Numeric (0 or 1). Patient has Primary Biliary Cholangitis (PBC) or Primary Sclerosing Cholangitis (PSC). (1 = Yes). If Yes, modified bilirubin thresholds are used (<4, 4-10, >10 mg/dL).

bilirubin_units

String. "mg/dL" (default) or "umol/L".

albumin_units

String. "g/dL" (default) or "g/L".

References

Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646-649. doi:10.1002/bjs.1800600817

Examples

# Example 1: Class A
# Bili 1.0, Alb 4.0, INR 1.0, No Ascites, No Enceph
child_pugh_score(1.0, 4.0, 1.0, "none", "none")

# Example 2: Class C
# Bili 4.0, Alb 2.0, INR 2.5, Moderate Ascites, Grade 3 Enceph
child_pugh_score(4.0, 2.0, 2.5, "moderate", "grade_3_4")