cliot (version 1.0.0)

ckd_epi_gfr: CKD-EPI Equations for Glomerular Filtration Rate (GFR)

Description

Calculates the Estimated Glomerular Filtration Rate (eGFR) using the CKD-EPI equations. This function includes the recommended 2021 Race-Free Creatinine equation, the 2021 Race-Free Creatinine-Cystatin C equation, the 2012 Cystatin C equation, and the older 2009 Race-Based Creatinine equation for comparison.

Usage

ckd_epi_gfr(age, sex, creatinine, cystatin_c = NULL, race_black = FALSE,
            creatinine_units = "mg/dL", cystatin_units = "mg/L")

Value

A list containing:

eGFR_2021_Creatinine

The current standard race-free estimate (mL/min/1.73m^2).

eGFR_2021_Creatinine_Cystatin_C

Combined race-free estimate (if Cystatin C provided).

eGFR_2012_Cystatin_C

Cystatin C only estimate (if provided).

eGFR_2009_Creatinine

The older race-based estimate.

Arguments

age

Numeric. Patient age in years.

sex

String. Patient sex ("Male" or "Female").

creatinine

Numeric. Serum Creatinine level.

cystatin_c

Numeric (Optional). Serum Cystatin C level. Required for Cystatin-based equations.

race_black

Numeric or Logical (0/1 or FALSE/TRUE). Patient is Black/African American. Used only for the 2009 equation; ignored by 2021 equations.

creatinine_units

String. Units for Creatinine. Options: "mg/dL" (default) or "micromol/L" (or "umol/L").

cystatin_units

String. Units for Cystatin C. Options: "mg/L" (default).

References

Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR Without Race. N Engl J Med. 2021;385:1737-1749. doi:10.1056/NEJMoa2102953 Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604-612.

Examples

# Example 1: Standard 2021 Creatinine (No Race Input Needed)
# Female, 58, Cr 0.9 mg/dL
ckd_epi_gfr(58, "female", 0.9)

# Example 2: Combined Creatinine-Cystatin C
# Male, 65, Cr 1.2 mg/dL, CysC 0.9 mg/L
ckd_epi_gfr(65, "male", 1.2, 0.9)

# Example 3: 2009 Comparison (Black Race)
# Male, 50, Cr 1.5 mg/dL, Race Black
ckd_epi_gfr(50, "male", 1.5, race_black = TRUE)